Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pergolide is dosed at 0.006–0.018 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Pergolide is used in dogs for Pituitary-dependent hyperadrenocorticism (investigational). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pergolide in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Prascend
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.006–0.018 mg/kg | q12h | Long-term | Pituitary-dependent hyperadrenocorticism (investigational) | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Potent dopamine D1 and D2 receptor agonist. Inhibits melanotrope proliferation in pars intermedia. First-line treatment for equine PPID (Cushing's).
FDA-approved for equine PPID (Prascend). Anorexia and depression common initially — start low and titrate. Monitor ACTH levels. Rarely used in small animals.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pergolide dose range in dogs, with cited source references: PO 0.006–0.018 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pergolide in dogs: PO.
Cited course lengths for Pergolide in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Pergolide is indicated in dogs for: Pituitary-dependent hyperadrenocorticism (investigational).
These are general warnings for Pergolide across species; consult the dog dosing table above for species-specific guidance. FDA-approved for equine PPID (Prascend). Anorexia and depression common initially — start low and titrate. Monitor ACTH levels. Rarely used in small animals.
Why a species-specific page? Pergolide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.