ExoticRx · exoticrx.com/drugs/pergolide
US brand names:Prascend
Pergolide is dosed at 0.006–0.018 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Potent dopamine D1 and D2 receptor agonist. Inhibits melanotrope proliferation in pars intermedia. First-line treatment for equine PPID (Cushing's).
FDA-approved for equine PPID (Prascend). Anorexia and depression common initially — start low and titrate. Monitor ACTH levels. Rarely used in small animals.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.006–0.018 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.