Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cloprostenol is dosed at 0.001–0.0025 mg/kg SC q24-48h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed, p. 300 (corpus PDF p. 327). Cloprostenol is used in dogs for Open pyometra, pregnancy termination. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Cloprostenol in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Estrumate
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 0.001–0.0025 mg/kg | q24-48h | 3-5 doses | Open pyometra, pregnancy termination | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed, p. 300 (corpus PDF p. 327) |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic prostaglandin F2α analog causing luteolysis (destruction of corpus luteum). Much more potent than natural PGF2α.
Handle with extreme caution — can cause abortion in pregnant women through skin absorption. Wear gloves. Bronchoconstriction risk in asthmatic handlers.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cloprostenol dose range in dogs, with cited source references: SC 0.001–0.0025 mg/kg q24-48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cloprostenol in dogs: SC.
Cited course lengths for Cloprostenol in dogs include: 3-5 doses. Duration depends on the indication — match it to the specific dose rule in the table above.
Cloprostenol is indicated in dogs for: Open pyometra, pregnancy termination.
These are general warnings for Cloprostenol across species; consult the dog dosing table above for species-specific guidance. Handle with extreme caution — can cause abortion in pregnant women through skin absorption. Wear gloves. Bronchoconstriction risk in asthmatic handlers.
Why a species-specific page? Cloprostenol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.