Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Liothyronine is dosed at 4–6 mcg/kg PO q8h in dogs, per Scott-Moncrieff JC. Chapter 3: Hypothyroidism. In: Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.793 (2026-08-01).. Liothyronine is used in dogs for Hypothyroidism (T3 supplementation). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Liothyronine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cytomel
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 4–6 mcg/kg | q8h | Long-term; levothyroxine generally preferred | Hypothyroidism (T3 supplementation) | Moderate | Scott-Moncrieff JC. Chapter 3: Hypothyroidism. In: Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.793 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic triiodothyronine (T3) that directly activates thyroid hormone receptors, increasing basal metabolic rate, protein synthesis, and oxygen consumption.
Short half-life requires multiple daily doses. Narrow therapeutic index. Used when levothyroxine alone is insufficient. Monitor thyroid levels.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Liothyronine dose range in dogs, with cited source references: PO 4–6 mcg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Liothyronine in dogs: PO.
Cited course lengths for Liothyronine in dogs include: Long-term; levothyroxine generally preferred. Duration depends on the indication — match it to the specific dose rule in the table above.
Liothyronine is indicated in dogs for: Hypothyroidism (T3 supplementation).
These are general warnings for Liothyronine across species; consult the dog dosing table above for species-specific guidance. Short half-life requires multiple daily doses. Narrow therapeutic index. Used when levothyroxine alone is insufficient. Monitor thyroid levels.
Why a species-specific page? Liothyronine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.