Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lyme Disease Vaccine (Borrelia) is dosed at 1 dose SC Annually before tick season in dogs, per 2022 AAHA Canine Vaccination Guidelines, American Animal Hospital Association (https://www.aaha.org/resources/2022-aaha-canine-vaccination-guidelines/), verified 2026-08-05. Lyme Disease Vaccine (Borrelia) is used in dogs for Lyme disease (high-risk booster), Lyme disease prevention. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Lyme Disease Vaccine (Borrelia) in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nobivac Lyme, Vanguard crLyme
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 1 dose | Annually before tick season | Annual booster; give before tick season for optimal protection | Lyme disease (high-risk booster) | Moderate | 2022 AAHA Canine Vaccination Guidelines, American Animal Hospital Association (https://www.aaha.org/resources/2022-aaha-canine-vaccination-guidelines/), verified 2026-08-05 |
| SC | 1 dose | 2 doses 2-4wk apart at 12wk; annually | Two-dose primary series; annual boosters in endemic areas | Lyme disease prevention | Moderate | 2022 AAHA Canine Vaccination Guidelines, American Animal Hospital Association (https://www.aaha.org/resources/2022-aaha-canine-vaccination-guidelines/), verified 2026-08-05; ACVIM Lyme Consensus |
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Enter your dog's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Recombinant OspA protein or killed whole-cell Borrelia burgdorferi inducing antibodies that kill spirochetes in the tick during feeding.
Recommended in endemic areas only. Two-dose primary series. Annual boosters required. Tick prevention still essential alongside vaccination.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Lyme Disease Vaccine (Borrelia) dose ranges in dogs, with cited source references: SC 1 dose Annually before tick season; SC 1 dose 2 doses 2-4wk apart at 12wk; annually. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Lyme Disease Vaccine (Borrelia) in dogs: SC.
Cited course lengths for Lyme Disease Vaccine (Borrelia) in dogs include: Annual booster; give before tick season for optimal protection; Two-dose primary series; annual boosters in endemic areas. Duration depends on the indication — match it to the specific dose rule in the table above.
Lyme Disease Vaccine (Borrelia) is indicated in dogs for: Lyme disease (high-risk booster), Lyme disease prevention.
These are general warnings for Lyme Disease Vaccine (Borrelia) across species; consult the dog dosing table above for species-specific guidance. Recommended in endemic areas only. Two-dose primary series. Annual boosters required. Tick prevention still essential alongside vaccination.
Why a species-specific page? Lyme Disease Vaccine (Borrelia) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.