Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Rifampin is dosed at 5–10 mg/kg PO q12-24h in dogs, per Hillier A, Lloyd DH, Weese JS, et al. Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis (antimicrobial guidelines working group of the international society for companion animal infectious diseases). Vet Dermatol. 2014;25(3):163-e43. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1147 (2026-08-01).. Rifampin is used in dogs for Staphylococcal infections (combination therapy). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Rifampin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rifadin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–10 mg/kg | q12-24h | Duration per primary antibiotic | Staphylococcal infections (combination therapy) | Moderate | Hillier A, Lloyd DH, Weese JS, et al. Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis (antimicrobial guidelines working group of the international society for companion animal infectious diseases). Vet Dermatol. 2014;25(3):163-e43. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1147 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial DNA-dependent RNA polymerase, blocking RNA synthesis. Excellent intracellular penetration.
Always use in combination (rapid resistance when used alone). Potent CYP inducer (many drug interactions). Orange/red discoloration of urine, tears. Hepatotoxic — monitor liver enzymes.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Rifampin dose range in dogs, with cited source references: PO 5–10 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Rifampin in dogs: PO.
Cited course lengths for Rifampin in dogs include: Duration per primary antibiotic. Duration depends on the indication — match it to the specific dose rule in the table above.
Rifampin is indicated in dogs for: Staphylococcal infections (combination therapy).
These are general warnings for Rifampin across species; consult the dog dosing table above for species-specific guidance. Always use in combination (rapid resistance when used alone). Potent CYP inducer (many drug interactions). Orange/red discoloration of urine, tears. Hepatotoxic — monitor liver enzymes.
Why a species-specific page? Rifampin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.