Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Rifampin is used in horse for Rhodococcus equi (with macrolide), abscess. Routes documented in horse: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Rifampin in horse, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Rifadin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–10 mg/kg | q12h | 4-12 weeks | Rhodococcus equi (with macrolide), abscess | Strong | Plumb's Veterinary Drug Handbook |
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These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial DNA-dependent RNA polymerase, blocking RNA synthesis. Excellent intracellular penetration.
Always use in combination (rapid resistance when used alone). Potent CYP inducer (many drug interactions). Orange/red discoloration of urine, tears. Hepatotoxic — monitor liver enzymes.
Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Rifampin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.