Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Mycophenolate Mofetil is dosed at 10–20 mg/kg PO q12h in dogs, per Abelson AL, Shelton GD, Whelan MF, Cornejo L, Shaw S, O'Toole TE. Use of mycophenolate mofetil as a rescue agent in the treatment of severe generalized myasthenia gravis in three dogs. J Vet Emerg Crit Care. 2009;19(4):369-374. doi:10.1111/j.1476-4431.2009.00433.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.949 (2026-08-01).. Mycophenolate Mofetil is used in dogs for IMHA, myasthenia gravis, immune-mediated skin disease. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Mycophenolate Mofetil in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: CellCept
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–20 mg/kg | q12h | Long-term | IMHA, myasthenia gravis, immune-mediated skin disease | Moderate | Abelson AL, Shelton GD, Whelan MF, Cornejo L, Shaw S, O'Toole TE. Use of mycophenolate mofetil as a rescue agent in the treatment of severe generalized myasthenia gravis in three dogs. J Vet Emerg Crit Care. 2009;19(4):369-374. doi:10.1111/j.1476-4431.2009.00433.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.949 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits inosine monophosphate dehydrogenase, selectively blocking de novo purine synthesis in lymphocytes (which lack the salvage pathway).
GI side effects common (diarrhea, vomiting). More selective immunosuppression than azathioprine. Monitor CBC. Teratogenic. Used for immune-mediated hemolytic anemia, myasthenia gravis, and transplant rejection.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Mycophenolate Mofetil dose range in dogs, with cited source references: PO 10–20 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Mycophenolate Mofetil in dogs: PO.
Cited course lengths for Mycophenolate Mofetil in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Mycophenolate Mofetil is indicated in dogs for: IMHA, myasthenia gravis, immune-mediated skin disease.
These are general warnings for Mycophenolate Mofetil across species; consult the dog dosing table above for species-specific guidance. GI side effects common (diarrhea, vomiting). More selective immunosuppression than azathioprine. Monitor CBC. Teratogenic. Used for immune-mediated hemolytic anemia, myasthenia gravis, and transplant rejection.
Why a species-specific page? Mycophenolate Mofetil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.