Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Mycophenolate Mofetil is dosed at 10–20 mg/kg PO q12h in dogs, per Abelson AL, Shelton GD, Whelan MF, Cornejo L, Shaw S, O'Toole TE. Use of mycophenolate mofetil as a rescue agent in the treatment of severe generalized myasthenia gravis in three dogs. J Vet Emerg Crit Care. 2009;19(4):369-374. doi:10.1111/j.1476-4431.2009.00433.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.949 (2026-08-01). — Plumb's 10th ed (held) printed p.921, Mycophenolate monograph spanning p.920-922; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Mycophenolate Mofetil is used in dogs for Myasthenia gravis; immune-mediated skin disease. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Mycophenolate Mofetil in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: CellCept
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–20 mg/kg | q12h | Long-term | Myasthenia gravis; immune-mediated skin disease | Moderate | Abelson AL, Shelton GD, Whelan MF, Cornejo L, Shaw S, O'Toole TE. Use of mycophenolate mofetil as a rescue agent in the treatment of severe generalized myasthenia gravis in three dogs. J Vet Emerg Crit Care. 2009;19(4):369-374. doi:10.1111/j.1476-4431.2009.00433.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.949 (2026-08-01). — Plumb's 10th ed (held) printed p.921, Mycophenolate monograph spanning p.920-922; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 8–12 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.294 | 8-12 mg/kg (typically 10 mg/kg) p.o., i.v. (give slowly over at least 2 hours) q12h (MMF), |
| 10 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.294 | 8-12 mg/kg (typically 10 mg/kg) p.o., i.v. (give slowly over at least 2 hours) q12h (MMF), the dose can be red |
| 7–13 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.294 | 7-13 mg/kg p.o. q8h (MMF). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits inosine monophosphate dehydrogenase, selectively blocking de novo purine synthesis in lymphocytes (which lack the salvage pathway).
GI side effects common (diarrhea, vomiting). More selective immunosuppression than azathioprine. Monitor CBC. Teratogenic. Used for immune-mediated hemolytic anemia, myasthenia gravis, and transplant rejection.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Mycophenolate Mofetil dose range in dogs, with cited source references: PO 10–20 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Mycophenolate Mofetil in dogs: PO.
Cited course lengths for Mycophenolate Mofetil in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Mycophenolate Mofetil is indicated in dogs for: Myasthenia gravis; immune-mediated skin disease.
These are general warnings for Mycophenolate Mofetil across species; consult the dog dosing table above for species-specific guidance. GI side effects common (diarrhea, vomiting). More selective immunosuppression than azathioprine. Monitor CBC. Teratogenic. Used for immune-mediated hemolytic anemia, myasthenia gravis, and transplant rejection.
Why a species-specific page? Mycophenolate Mofetil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 10 |
| PO |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.579 |
| • 10 mg/kg q8h PO, or 20 mg/kg q 8-12h PO. (As dose is increased, adverse |
| 20 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.579 | • 10 mg/kg q8h PO, or 20 mg/kg q 8-12h PO. (As dose is increased, adverse |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.