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Mycophenolate Mofetil

CellCept

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Immunosuppressant

Routes

POIV

Indications

IMHAImmune-mediated diseasesimmune-mediated skin diseasemyasthenia gravis

Mechanism of Action

Inhibits inosine monophosphate dehydrogenase, selectively blocking de novo purine synthesis in lymphocytes (which lack the salvage pathway).

Side effects & warnings

GI side effects common (diarrhea, vomiting). More selective immunosuppression than azathioprine. Monitor CBC. Teratogenic. Used for immune-mediated hemolytic anemia, myasthenia gravis, and transplant rejection.

Species with Mycophenolate Mofetil dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Moderate×1Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

  • · Papich Handbook of Veterinary Drugs, 5th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO10–20 mg/kgq12hModeratePlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO10 mg/kgq12hWeakPapich Handbook of Veterinary Drugs, 5th Ed

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