Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Doripenem is dosed at 8 mg/kg IV q8h in dogs, per Papich Handbook of Veterinary Drugs, 5th Ed, printed p.269 (corpus p.297), Doripenem, Small Animal Dosage — EDITION CORRECTED 2026-08-07: this citation named the 5th edition, which is not held. The page locator resolves in the 4th ed (2016), the copy actually consulted, and that page names the drug; the reference is to the 4th. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Doripenem is used in dogs for Severe gram-negative/mixed infections. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Doripenem in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Doribax
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 8 mg/kg | q8h | 5-14 days | Severe gram-negative/mixed infections | Weak |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 8 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.297 | • 8 mg/kg q8h IV. Infuse over 30 minutes to 1 hour. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds PBPs inhibiting cell wall synthesis. Broad-spectrum carbapenem with stability against some carbapenemases.
Seizure risk in CNS disorders. Renal dose adjustment required. GI upset. Very limited veterinary data.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Doripenem dose range in dogs, with cited source references: IV 8 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Doripenem in dogs: IV.
Cited course lengths for Doripenem in dogs include: 5-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Doripenem is indicated in dogs for: Severe gram-negative/mixed infections.
These are general warnings for Doripenem across species; consult the dog dosing table above for species-specific guidance. Seizure risk in CNS disorders. Renal dose adjustment required. GI upset. Very limited veterinary data.
Why a species-specific page? Doripenem pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.