Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Selamectin is dosed at 6–12 mg/kg TOPICAL q30d in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.749 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.749' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.721; verified by finding the drug named there. If you are holding the book, turn to p.721. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Selamectin is used in dogs for Heartworm prevention, fleas, ear mites, sarcoptic mange. Routes documented in dogs: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Selamectin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Revolution, Stronghold
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 6–12 mg/kg | q30d | Monthly topical | Heartworm prevention, fleas, ear mites, sarcoptic mange | Strong | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.749 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.749' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.721; verified by finding the drug named there. If you are holding the book, turn to p.721. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 6 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.387 | minimum dose recommendation 6 mg/kg. For flea and heartworm prevention apply monthly. For the treatment of roundworms, hookwo |
| 6–12 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.749 | • Sarcoptic mange treatment: 6-12 mg/kg twice 30 days apart. (However, many |
| 6 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.749 | 6 mg/kg every 30 days. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Absorbed through skin; reaches systemic circulation.
Do not apply to broken skin. Monthly application. Prevents heartworm, kills fleas, treats ear mites, sarcoptic mange. Safe in MDR1 dogs at labeled dose. OK in rabbits and ferrets.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Selamectin dose range in dogs, with cited source references: TOPICAL 6–12 mg/kg q30d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Selamectin in dogs: TOPICAL.
Cited course lengths for Selamectin in dogs include: Monthly topical. Duration depends on the indication — match it to the specific dose rule in the table above.
Selamectin is indicated in dogs for: Heartworm prevention, fleas, ear mites, sarcoptic mange.
These are general warnings for Selamectin across species; consult the dog dosing table above for species-specific guidance. Do not apply to broken skin. Monthly application. Prevents heartworm, kills fleas, treats ear mites, sarcoptic mange. Safe in MDR1 dogs at labeled dose. OK in rabbits and ferrets.
Why a species-specific page? Selamectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.