Cat · Felis catus · typical adult weight 2.50–7.00 kg
Selamectin is dosed at 6–12 mg/kg TOPICAL q30d in cats, per Koch S, Torres S, Plumb D. Small Animal Dermatology Drug Handbook. Wiley-Blackwell; 2011. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1175 (2026-08-01). — Plumb's 10th ed (held) printed p.1148, Selamectin monograph spanning p.1147-1148; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Muller & Kirk's Small Animal Dermatology — ISBN 9781416000280, https://openlibrary.org/isbn/9781416000280 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 1 — "6 - 13 mg/kg topically every 2 vation and vomiting1 ; anorexia and let" — which resolves in the monograph's own reference list to: REVOLUTION PLUS - Selamectin and Sarolaner Solution [US Product Label for Cats]. Zoetis Inc.; 2019. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.. Selamectin is used in cats for Heartworm prevention, flea control (monthly). Routes documented in cats: TOPICAL. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Selamectin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Revolution, Stronghold
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 6–12 mg/kg | q30d | Monthly topical | Heartworm prevention, flea control (monthly) | Strong | Koch S, Torres S, Plumb D. Small Animal Dermatology Drug Handbook. Wiley-Blackwell; 2011. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1175 (2026-08-01). — Plumb's 10th ed (held) printed p.1148, Selamectin monograph spanning p.1147-1148; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Muller & Kirk's Small Animal Dermatology — ISBN 9781416000280, https://openlibrary.org/isbn/9781416000280 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 1 — "6 - 13 mg/kg topically every 2 vation and vomiting1 ; anorexia and let" — which resolves in the monograph's own reference list to: REVOLUTION PLUS - Selamectin and Sarolaner Solution [US Product Label for Cats]. Zoetis Inc.; 2019. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 6 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.387 | minimum dose recommendation 6 mg/kg. For flea and heartworm prevention apply monthly. For the treatment of roundworms, hookwo |
| 6–12 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.749 | • Sarcoptic mange treatment: 6-12 mg/kg twice 30 days apart. (However, many |
| 6 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.749 | 6 mg/kg every 30 days. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Absorbed through skin; reaches systemic circulation.
Do not apply to broken skin. Monthly application. Prevents heartworm, kills fleas, treats ear mites, sarcoptic mange. Safe in MDR1 dogs at labeled dose. OK in rabbits and ferrets.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Selamectin dose range in cats, with cited source references: TOPICAL 6–12 mg/kg q30d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Selamectin in cats: TOPICAL.
Cited course lengths for Selamectin in cats include: Monthly topical. Duration depends on the indication — match it to the specific dose rule in the table above.
Selamectin is indicated in cats for: Heartworm prevention, flea control (monthly).
These are general warnings for Selamectin across species; consult the cat dosing table above for species-specific guidance. Do not apply to broken skin. Monthly application. Prevents heartworm, kills fleas, treats ear mites, sarcoptic mange. Safe in MDR1 dogs at labeled dose. OK in rabbits and ferrets.
Why a species-specific page? Selamectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.