Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.
Selamectin is dosed at 6–15 mg/kg TOPICAL q30d (monthly) in rabbits, per BSAVA Small Animal Formulary, 10th Ed, Part B: Exotic Pets (ed. Joanna Hedley), Selamectin (Stronghold), DOSES, printed p.265: 'Mammals: Ferrets, Rabbits, Rodents: 6-15 mg/kg monthly; Sugar gliders, Hedgehogs: 6-18 mg/kg monthly.'. Verify against current literature before clinical use.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Absorbed through skin; reaches systemic circulation.
Side effects & warnings
Do not apply to broken skin. Monthly application. Prevents heartworm, kills fleas, treats ear mites, sarcoptic mange. Safe in MDR1 dogs at labeled dose. OK in rabbits and ferrets.
Species with Selamectin dosing data (9 dose rules)
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Sample dosing (2 of 9 cited rules)
A dog/cat sample is shown here. Cited dosing for all 9 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Koch S, Torres S, Plumb D. Small Animal Dermatology Drug Handbook. Wiley-Blackwell; 2011. — Plumb's 10th ed printed p.1148, Selamectin monograph spanning p.1147-1148. | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 1 — "6 - 13 mg/kg topically every 2 vation and vomiting1; anorexia and let" — which resolves in the monograph's own reference list to: REVOLUTION PLUS - Selamectin and Sarolaner Solution [US Product Label for Cats]. Zoetis Inc.; 2019. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.Compilation only — we have not located an independent source that prints this figure.
· Eshar D, Bdolah-Abram T. Comparison of efficacy, safety, and convenience of selamectin versus ivermectin for treatment of Trixacarus caviae mange in pet guinea pigs (Cavia porcellus). J Am Vet Med Assoc. 2012;241:1056-1058. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.780 doi:10.2460/javma.241.8.1056 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.2 (Antiparasitic Agents Used in Rodents).
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Ewringmann A, Gloeckner B. Leitsymptome bei Hamster, Ratte, Maus und Rennmaus, Enke, Stuttgart, Germany; 2014. | Fehr M, Sassenburg L, Zwart P. Krankheiten der Heimtiere, 8th ed., Schluetersche Verlagsgesellschaft, Hannover, Germany; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.780 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.2 (Antiparasitic Agents Used in Rodents).
· Ewringmann A, Gloeckner B. Leitsymptome bei Hamster, Ratte, Maus und Rennmaus. — Carpenter's Exotic Animal Formulary 6th ed, Table 9.2 (Antiparasitic Agents Used in Rodents).
· Koch S, Torres S, Plumb D. Small Animal Dermatology Drug Handbook. Wiley-Blackwell; 2011. — Plumb's 10th ed printed p.1148, Selamectin monograph spanning p.1147-1148. | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 1 — "6 - 13 mg/kg topically every 2 vation and vomiting1; anorexia and let" — which resolves in the monograph's own reference list to: REVOLUTION PLUS - Selamectin and Sarolaner Solution [US Product Label for Cats]. Zoetis Inc.; 2019. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.
· Morrisey JK. Ectoparasites of ferrets and rabbits. Proc North Am Vet Conf; 1998:844-845. — Carpenter's Exotic Animal Formulary 6th ed, Table 11.4 (Antiparasitic Agents Used in Ferrets).
· Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.721
· Vogelnest L. Dermatology. In: Vogelnest L, Portas T, eds. Current Therapy in Medicine of Australian Mammals; CSIRO Publishing, Clayton South, Vic; 2019:181-206. — Carpenter's Exotic Animal Formulary 6th ed, Table 7.2 (Antiparasitic Agents Used in Sugar Gliders).