Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Toceranib is used in dog for Mast cell tumors, Mast cell tumors, various carcinomas. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Toceranib in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Palladia, Palladia Oral Solution, Palladia (Toceranib Phosphate Solution)
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2.5–3.25 mg/kg | q48h (every other day) | Long-term | Mast cell tumors | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 2.5–3.25 mg/kg | q48h (every other day) | Until progression or intolerance | Mast cell tumors, various carcinomas | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Multi-target TKI inhibiting c-Kit, VEGFR2, PDGFR-beta, and other kinases. Anti-tumor and anti-angiogenic activity.
FDA-approved for canine mast cell tumors (Palladia). GI toxicity, neutropenia, GI perforation, hypertension. Monitor CBC, blood pressure, urinalysis. Every-other-day dosing.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Toceranib pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.