Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Moxidectin is dosed at 0.17 mg/kg SC q6 months (ProHeart 6) in dogs, per Plumb's Veterinary Drug Handbook, 10th ed. (2023), printed p.915 (corpus PDF p.942), DOGS / ProHeart 6 and ProHeart 12 label dosage (FDA-approved).. Moxidectin is used in dogs for Heartworm prevention (6- or 12-month). Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Moxidectin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: ProHeart, Advantage Multi, ProHeart 6, ProHeart 12
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 0.17 mg/kg | q6 months (ProHeart 6) | 6- or 12-month injection | Heartworm prevention (6- or 12-month) | Strong | Plumb's Veterinary Drug Handbook, 10th ed. (2023), printed p.915 (corpus PDF p.942), DOGS / ProHeart 6 and ProHeart 12 label dosage (FDA-approved). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Sustained-release formulation provides 6- or 12-month heartworm prevention.
Caution in MDR1-mutant dogs. ProHeart injection: risk of anaphylaxis (monitor 30 min post-injection). Test for heartworm before starting. Store properly.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Moxidectin dose range in dogs, with cited source references: SC 0.17 mg/kg q6 months (ProHeart 6). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Moxidectin in dogs: SC.
Cited course lengths for Moxidectin in dogs include: 6- or 12-month injection. Duration depends on the indication — match it to the specific dose rule in the table above.
Moxidectin is indicated in dogs for: Heartworm prevention (6- or 12-month).
These are general warnings for Moxidectin across species; consult the dog dosing table above for species-specific guidance. Caution in MDR1-mutant dogs. ProHeart injection: risk of anaphylaxis (monitor 30 min post-injection). Test for heartworm before starting. Store properly.
Why a species-specific page? Moxidectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.