Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Moxidectin is dosed at 0.2 mg/kg SC single dose in cattle, per CYDECTIN INJECTION FOR BEEF AND NONLACTATING DAIRY CATTLE - Moxidectin Injection, Solution [US Product Label]. Elanco US Inc.; 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.943 (2026-08-01). — Plumb's 10th ed (held) printed p.916, Moxidectin/Moxidectin Combination Products monograph spanning p.912-917; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Moxidectin is used in cattle for Internal and external parasites. Routes documented in cattle: SC. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Moxidectin in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: ProHeart, Advantage Multi, ProHeart 6, ProHeart 12
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 0.2 mg/kg | single dose | Internal and external parasites | Strong | CYDECTIN INJECTION FOR BEEF AND NONLACTATING DAIRY CATTLE - Moxidectin Injection, Solution [US Product Label]. Elanco US Inc.; 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.943 (2026-08-01). — Plumb's 10th ed (held) printed p.916, Moxidectin/Moxidectin Combination Products monograph spanning p.912-917; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.2 | SC | Papich Saunders Handbook of Veterinary Drugs, 4th edp.576 | • 0.2 mg/kg SQ once. |
| 0.5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.576 | 0.5 mg/kg (0.23 mg/lb or 45 mL per 1000 lbs). Apply topically along the midline |
| Dose (mg/lb) | Route | Source | As printed |
|---|---|---|---|
| 0.23 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.576 | 0.5 mg/kg (0.23 mg/lb or 45 mL per 1000 lbs). Apply topically along the midline |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Sustained-release formulation provides 6- or 12-month heartworm prevention.
Caution in MDR1-mutant dogs. ProHeart injection: risk of anaphylaxis (monitor 30 min post-injection). Test for heartworm before starting. Store properly.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Moxidectin dose range in cattle, with cited source references: SC 0.2 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Moxidectin in cattle: SC.
Moxidectin is indicated in cattle for: Internal and external parasites.
These are general warnings for Moxidectin across species; consult the cattle dosing table above for species-specific guidance. Caution in MDR1-mutant dogs. ProHeart injection: risk of anaphylaxis (monitor 30 min post-injection). Test for heartworm before starting. Store properly.
Why a species-specific page? Moxidectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.