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Eprinomectin (Pour-On) for Cattle

Livestock · Bos taurus · typical adult weight 250.00–900.00 kg

Eprinomectin (Pour-On) is used in cattle for Internal and external parasites, GI nematodes, lungworms, grubs, lice. Routes documented in cattle: TOPICAL. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Eprinomectin (Pour-On) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Eprinex, Ivomec Eprinex

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
TOPICAL0.5 mg/kgsingle pour-on applicationInternal and external parasitesStrongFDA NADA Label
TOPICAL0.5 mg/kgOnceSingle applicationGI nematodes, lungworms, grubs, liceStrongFDA NADA Label

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These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Macrocyclic lactone that potentiates glutamate-gated chloride channels in nematode and arthropod nerve/muscle cells, causing paralysis and death of parasites.

Side effects & warnings

Zero-day milk and meat withdrawal in dairy cattle at label dose — unique advantage over other avermectins. For topical application along the backline. Not for use in calves under 200 lbs intended for veal.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antiparasitic drugs with cattle dosing

Why a species-specific page? Eprinomectin (Pour-On) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.