ExoticRx · exoticrx.com/drugs/moxidectin
US brand names:ProHeart, Advantage Multi(combination), ProHeart 6, ProHeart 12
Moxidectin is dosed at 0.17 mg/kg SC q6-12months in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Sustained-release formulation provides 6- or 12-month heartworm prevention.
Caution in MDR1-mutant dogs. ProHeart injection: risk of anaphylaxis (monitor 30 min post-injection). Test for heartworm before starting. Store properly.
Species references:All Cattle (Beef/Dairy) drugsAll Dog (Domestic) drugsAll Goat (Caprine) drugsAll Horse (Equine) drugsAll Sheep (Ovine) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 5 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 0.17 mg/kg | q6-12months | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.