Pasireotide for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pasireotide is used in dog for Pituitary-dependent hyperadrenocorticism. Routes documented in dog: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pasireotide in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Signifor
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 0.03–0.1 mg/kg | q12h (SC) or monthly (LAR) | Investigational; long-term for Cushing's | Pituitary-dependent hyperadrenocorticism | Weak | Veterinary Endocrinology Literature Review |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Somatostatin analogue with broad somatostatin receptor affinity (SST1,2,3,5) that suppresses ACTH secretion from corticotroph adenomas.
Side effects & warnings
Hyperglycemia is very common. Monitor blood glucose. Investigational for pituitary-dependent hyperadrenocorticism in dogs.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Endocrine drugs with dog dosing
Pasireotide dosing in other species
Why a species-specific page? Pasireotide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.