Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Verdinexor is used in dog for Canine lymphoma. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Verdinexor in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Laverdia-CA1
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1.5 mg/kg | Monday and Wednesday each week | Continue until progression or intolerance | Canine lymphoma | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selectively inhibits XPO1 (exportin 1), trapping tumor suppressor proteins in the nucleus and restoring cell cycle control and apoptosis in neoplastic cells.
Dogs only. GI toxicity (anorexia, vomiting, diarrhea, weight loss). Monitor CBC and liver values. Approved for canine lymphoma.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Verdinexor pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.