Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Verdinexor is dosed at 1.25–1.5 mg/kg PO twice weekly, >=72h apart (eg Mon & Thu) in dogs, per Plumb's Veterinary Drug Handbook 9th ed, Verdinexor, Dosages > DOGS, printed p.1301 (corpus 1328); LAVERDIA-CA1 US Product Label, Anivive Lifesciences, 2021. Verdinexor is used in dogs for Canine lymphoma. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Verdinexor in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Laverdia-CA1
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1.25–1.5 mg/kg | twice weekly, >=72h apart (eg Mon & Thu) | Continue until progression or intolerance | Canine lymphoma | Moderate | Plumb's Veterinary Drug Handbook 9th ed, Verdinexor, Dosages > DOGS, printed p.1301 (corpus 1328); LAVERDIA-CA1 US Product Label, Anivive Lifesciences, 2021 |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selectively inhibits XPO1 (exportin 1), trapping tumor suppressor proteins in the nucleus and restoring cell cycle control and apoptosis in neoplastic cells.
Dogs only. GI toxicity (anorexia, vomiting, diarrhea, weight loss). Monitor CBC and liver values. Approved for canine lymphoma.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Verdinexor dose range in dogs, with cited source references: PO 1.25–1.5 mg/kg twice weekly, >=72h apart (eg Mon & Thu). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Verdinexor in dogs: PO.
Cited course lengths for Verdinexor in dogs include: Continue until progression or intolerance. Duration depends on the indication — match it to the specific dose rule in the table above.
Verdinexor is indicated in dogs for: Canine lymphoma.
These are general warnings for Verdinexor across species; consult the dog dosing table above for species-specific guidance. Dogs only. GI toxicity (anorexia, vomiting, diarrhea, weight loss). Monitor CBC and liver values. Approved for canine lymphoma.
Why a species-specific page? Verdinexor pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.