ExoticRx · exoticrx.com/drugs/verdinexor
US brand names:Laverdia-CA1
Verdinexor is dosed at 1.25–1.5 mg/kg PO twice weekly, >=72h apart (eg Mon & Thu) in dogs, per Plumb's Veterinary Drug Handbook 9th ed, Verdinexor, Dosages > DOGS, printed p.1301 (corpus 1328); LAVERDIA-CA1 US Product Label, Anivive Lifesciences, 2021. Verify against current literature before clinical use.
Selectively inhibits XPO1 (exportin 1), trapping tumor suppressor proteins in the nucleus and restoring cell cycle control and apoptosis in neoplastic cells.
Dogs only. GI toxicity (anorexia, vomiting, diarrhea, weight loss). Monitor CBC and liver values. Approved for canine lymphoma.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1.25–1.5 mg/kg | twice weekly, >=72h apart (eg Mon & Thu) | Moderate | Plumb's Veterinary Drug Handbook 9th ed, Verdinexor, Dosages > DOGS, printed p.1301 (corpus 1328); LAVERDIA-CA1 US Product Label, Anivive Lifesciences, 2021 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.