Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Vatinoxan is used in dogs for Used with medetomidine (Zenalpha) for sedation with reduced CV effects. Routes documented in dogs: IM. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Vatinoxan in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zenalpha
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | Dosing: per Zenalpha label (combined product) | Single dose | Duration of sedation | Used with medetomidine (Zenalpha) for sedation with reduced CV effects | Strong | ZENALPHA- Vatinoxan Hydrochloride and Medetomidine Hydrochloride Solution [US Product Label for Dogs]. Dechra Veterinary Products; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=623f44bf-07c7-4704-8114-5e42e1316fb1 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.840 (2026-08-01). |
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Peripheral alpha-2 adrenergic antagonist that does not cross BBB. Blocks cardiovascular side effects of medetomidine (bradycardia, vasoconstriction) while preserving central sedation.
Dogs only. FDA-approved in combination with medetomidine. Preserves sedation while reducing cardiovascular compromise. Do not use additional atipamezole peripherally.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Vatinoxan dose range in dogs, with cited source references: IM Dosing: per Zenalpha label (combined product) Single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Vatinoxan in dogs: IM.
Cited course lengths for Vatinoxan in dogs include: Duration of sedation. Duration depends on the indication — match it to the specific dose rule in the table above.
Vatinoxan is indicated in dogs for: Used with medetomidine (Zenalpha) for sedation with reduced CV effects.
These are general warnings for Vatinoxan across species; consult the dog dosing table above for species-specific guidance. Dogs only. FDA-approved in combination with medetomidine. Preserves sedation while reducing cardiovascular compromise. Do not use additional atipamezole peripherally.
Why a species-specific page? Vatinoxan pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.