ExoticRx · exoticrx.com/drugs/vatinoxan
US brand names:Zenalpha(with medetomidine)
Peripheral alpha-2 adrenergic antagonist that does not cross BBB. Blocks cardiovascular side effects of medetomidine (bradycardia, vasoconstriction) while preserving central sedation.
Dogs only. FDA-approved in combination with medetomidine. Preserves sedation while reducing cardiovascular compromise. Do not use additional atipamezole peripherally.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | Dosing: per Zenalpha label (combined product) | Single dose | Strong | ZENALPHA- Vatinoxan Hydrochloride and Medetomidine Hydrochloride Solution [US Product Label for Dogs]. Dechra Veterinary Products; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=623f44bf-07c7-4704-8114-5e42e1316fb1 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.840 (2026-08-01). |
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