ExoticRx · exoticrx.com/drugs/vatinoxan
US brand names:Zenalpha(with medetomidine)
Peripheral alpha-2 adrenergic antagonist that does not cross BBB. Blocks cardiovascular side effects of medetomidine (bradycardia, vasoconstriction) while preserving central sedation.
Dogs only. FDA-approved in combination with medetomidine. Preserves sedation while reducing cardiovascular compromise. Do not use additional atipamezole peripherally.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | See the cited source for the printed regimen | Single dose | Strong | ZENALPHA- Vatinoxan Hydrochloride and Medetomidine Hydrochloride Solution [US Product Label for Dogs]. Dechra Veterinary Products; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=623f44bf-07c7-4704-8114-5e42e1316fb1 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.840 (2026-08-01). — Plumb's 10th ed (held) printed p.811, Medetomidine/Vatinoxan monograph spanning p.811-813; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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