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Detomidine (Injectable)

Dormosedan

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Sedative

Routes

IVIMSublingual

Indications

analgesiaSedationStanding sedation

Mechanism of Action

Potent alpha-2 adrenoceptor agonist providing dose-dependent sedation and analgesia. More potent than xylazine. Acts on central and peripheral alpha-2 receptors.

Side effects & warnings

Causes initial hypertension followed by hypotension and bradycardia. Transient second-degree AV block is common. Reduce doses of other CNS depressants. Atipamezole reversal available but not labeled for horses.

Species with Detomidine (Injectable) dosing data (3 dose rules)

Cattle (Beef/Dairy)Horse (Equine)

Species references:All Cattle (Beef/Dairy) drugsAll Horse (Equine) drugs

Evidence levels across 3 dose rules

Moderate×1Strong×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

  • · FDA NADA Label
  • · Plumb's Veterinary Drug Handbook, 9th Ed

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