ExoticRx · exoticrx.com/drugs/medetomidine-vatinoxan
Zenalpha
Medetomidine provides alpha-2 mediated sedation and analgesia; vatinoxan blocks peripheral alpha-2 effects to maintain cardiac output and tissue perfusion.
Dogs only (FDA-approved). Reduced bradycardia compared to medetomidine alone. Reversible with atipamezole for central effects. Improved hemodynamic profile.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 0 per Zenalpha label | Single dose (weight-based) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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