Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Detomidine (Injectable) is dosed at 0.02–0.04 mg/kg IM single dose in horses, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.386 (2026-08-01).. Detomidine (Injectable) is used in horses for Standing sedation, Sedation, analgesia. Routes documented in horses: IM, IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Detomidine (Injectable) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Dormosedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.02–0.04 mg/kg | single dose | Standing sedation | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.386 (2026-08-01). |
| IV | 0.01–0.04 mg/kg | single dose | Sedation, analgesia | Strong | DORMOSEDAN STERILE- detomidine hydrochloride solution [US product label]. Kalamazoo, MI: Zoetis Inc; 2018. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0effd774-601f-4019-a1f3-350e47835967 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.386 (2026-08-01). |
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Potent alpha-2 adrenoceptor agonist providing dose-dependent sedation and analgesia. More potent than xylazine. Acts on central and peripheral alpha-2 receptors.
Causes initial hypertension followed by hypotension and bradycardia. Transient second-degree AV block is common. Reduce doses of other CNS depressants. Atipamezole reversal available but not labeled for horses.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Detomidine (Injectable) dose ranges in horses, with cited source references: IM 0.02–0.04 mg/kg single dose; IV 0.01–0.04 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Detomidine (Injectable) in horses: IM, IV.
Detomidine (Injectable) is indicated in horses for: Standing sedation, Sedation, analgesia.
These are general warnings for Detomidine (Injectable) across species; consult the horse dosing table above for species-specific guidance. Causes initial hypertension followed by hypotension and bradycardia. Transient second-degree AV block is common. Reduce doses of other CNS depressants. Atipamezole reversal available but not labeled for horses.
Why a species-specific page? Detomidine (Injectable) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.