Skip to main content

Acepromazine (Livestock) for Horse

Equine · Equus caballus · typical adult weight 350.00–700.00 kg

Acepromazine (Livestock) is used in horse for Sedation, preanesthetic, Pre-anesthetic sedation. Routes documented in horse: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Acepromazine (Livestock) in horse, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: PromAce, Atravet

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV0.02–0.05 mg/kgsingle doseSedation, preanestheticStrongPlumb's Veterinary Drug Handbook, 9th Ed
IV0.02–0.05 mg/kgAs neededSingle dose; 30-60 minPre-anesthetic sedationStrongPlumb's Veterinary Drug Handbook

Need the exact dose for your patient?

These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

Calculate for this horse

Mechanism of action

Phenothiazine derivative that blocks postsynaptic dopamine receptors in the CNS, producing sedation and reducing anxiety. Also has antiemetic and mild antihistaminic effects.

Side effects & warnings

Causes hypotension by alpha-1 adrenergic blockade. Do not use in stallions (penile prolapse risk). No analgesic properties. Avoid in hypovolemic or debilitated animals. Long duration of action.

Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Sedative drugs with horse dosing

Acepromazine (Livestock) dosing in other species

Why a species-specific page? Acepromazine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.