Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Acepromazine (Livestock) is dosed at 0.02–0.05 mg/kg IV Single slow IV dose, do not repeat within 36 hours in horses, per Atravet - acepromazine maleate 10 mg Injection [Canadian product label for cattle, sheep, goats, and horses]. Published online 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01). — Plumb's 10th ed (held) printed p.2, Acepromazine monograph spanning p.2-6; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Acepromazine (Livestock) is used in horses for Pre-anesthetic sedation, Sedation, preanesthetic. Routes documented in horses: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Acepromazine (Livestock) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: PromAce, Atravet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.02–0.05 mg/kg | Single slow IV dose, do not repeat within 36 hours | Single dose; 30-60 min | Pre-anesthetic sedation | Strong | Atravet - acepromazine maleate 10 mg Injection [Canadian product label for cattle, sheep, goats, and horses]. Published online 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01). — Plumb's 10th ed (held) printed p.2, Acepromazine monograph spanning p.2-6; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| IV | 0.02–0.05 mg/kg | single dose | — | Sedation, preanesthetic | Strong | ACP 10 Anaesthetic Premedication, Tranquilliser and Travel Sickness Sterile Injection [Australian product label for horses, cattle, pigs, and sheep]. Published online 2016. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01). — Plumb's 10th ed (held) printed p.2, Acepromazine monograph spanning p.2-6; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.04–0.1 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.30 | • 0.04-0.1 mg/kg IM, q 6-12h, but frequent dosing is not recommended, and an |
| 0.01–0.05 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.30 | 0.01-0.05 mg/kg, IM, SQ, or IV. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Phenothiazine derivative that blocks postsynaptic dopamine receptors in the CNS, producing sedation and reducing anxiety. Also has antiemetic and mild antihistaminic effects.
Causes hypotension by alpha-1 adrenergic blockade. Do not use in stallions (penile prolapse risk). No analgesic properties. Avoid in hypovolemic or debilitated animals. Long duration of action.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Acepromazine (Livestock) dose ranges in horses, with cited source references: IV 0.02–0.05 mg/kg Single slow IV dose, do not repeat within 36 hours; IV 0.02–0.05 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Acepromazine (Livestock) in horses: IV.
Cited course lengths for Acepromazine (Livestock) in horses include: Single dose; 30-60 min. Duration depends on the indication — match it to the specific dose rule in the table above.
Acepromazine (Livestock) is indicated in horses for: Pre-anesthetic sedation, Sedation, preanesthetic.
These are general warnings for Acepromazine (Livestock) across species; consult the horse dosing table above for species-specific guidance. Causes hypotension by alpha-1 adrenergic blockade. Do not use in stallions (penile prolapse risk). No analgesic properties. Avoid in hypovolemic or debilitated animals. Long duration of action.
Why a species-specific page? Acepromazine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.