Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Acepromazine (Livestock) is dosed at 0.05–0.1 mg/kg IM As needed in cattle, per Booth NH. Drugs acting on the central nervous system. In: Booth NH, McDonald LE, eds. Veterinary Pharmacology and Therapeutics. 6th ed. Iowa State University Press; 1988:153-408. doi:10.52458/9789391842529.nsp2022.eb.asu.ch10 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01).. Acepromazine (Livestock) is used in cattle for Sedation, pre-anesthetic, Sedation. Routes documented in cattle: IM, IV. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Acepromazine (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: PromAce, Atravet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.05–0.1 mg/kg | As needed | Single dose | Sedation, pre-anesthetic | Moderate |
| Booth NH. Drugs acting on the central nervous system. In: Booth NH, McDonald LE, eds. Veterinary Pharmacology and Therapeutics. 6th ed. Iowa State University Press; 1988:153-408. doi:10.52458/9789391842529.nsp2022.eb.asu.ch10 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01). |
| IV | 0.02–0.05 mg/kg | single dose | — | Sedation | Moderate | Clarke KW, Trim CM, Hall LW, eds. Chapter 12 - Anaesthesia of cattle. In: Veterinary Anaesthesia (Eleventh Edition). W.B. Saunders; 2014:313-343. doi:10.1016/b978-0-7020-2793-2.00012-8 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01). |
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These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Phenothiazine derivative that blocks postsynaptic dopamine receptors in the CNS, producing sedation and reducing anxiety. Also has antiemetic and mild antihistaminic effects.
Causes hypotension by alpha-1 adrenergic blockade. Do not use in stallions (penile prolapse risk). No analgesic properties. Avoid in hypovolemic or debilitated animals. Long duration of action.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Acepromazine (Livestock) dose ranges in cattle, with cited source references: IM 0.05–0.1 mg/kg As needed; IV 0.02–0.05 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Acepromazine (Livestock) in cattle: IM, IV.
Cited course lengths for Acepromazine (Livestock) in cattle include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Acepromazine (Livestock) is indicated in cattle for: Sedation, pre-anesthetic, Sedation.
These are general warnings for Acepromazine (Livestock) across species; consult the cattle dosing table above for species-specific guidance. Causes hypotension by alpha-1 adrenergic blockade. Do not use in stallions (penile prolapse risk). No analgesic properties. Avoid in hypovolemic or debilitated animals. Long duration of action.
Why a species-specific page? Acepromazine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.