What is the dose of Xylazine for Cattle?

Xylazine dose ranges in cattle, with cited primary-source references: IM 0.1–0.2 mg/kg single dose; IV 0.05–0.1 mg/kg single dose.

How is Xylazine administered in Cattle?

Documented routes for Xylazine in cattle: IM, IV.

What conditions does Xylazine treat in Cattle?

Xylazine is indicated in cattle for: Sedation, Sedation, analgesia.

Xylazine for Cattle

Livestock · Bos taurus · typical adult weight 250.00–900.00 kg

Xylazine is used in cattle for Sedation, Sedation, analgesia. Routes documented in cattle: IM, IV. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Xylazine in cattle, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Rompun, AnaSed

Dose ranges

Route	Dose	Frequency	Indication	Evidence	Source
IM	0.1–0.2 mg/kg	single dose	Sedation	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
IV	0.05–0.1 mg/kg	single dose	Sedation, analgesia	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Alpha-2 adrenergic agonist causing dose-dependent sedation, analgesia, and muscle relaxation. Also activates peripheral alpha-2 receptors causing vasoconstriction and bradycardia.

Side effects & warnings

Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Sedative drugs with cattle dosing

Acepromazine (Livestock)Detomidine Detomidine (Injectable)Diazepam

Xylazine dosing in other species

Goat Sheep Swine Cat Dog Horse Pet Rat

See all species for Xylazine See all drugs for Cattle

Why a species-specific page? Xylazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.