Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Xylazine is dosed at 0.1–0.2 mg/kg IM single dose in cattle, per Walz P. Practical management of pain in cattle. Presented at: ABVP; 2006. PMID: 42126006 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1349 (2026-08-01).. Xylazine is used in cattle for Sedation, Sedation, analgesia. Routes documented in cattle: IM, IV. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Xylazine in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rompun, AnaSed
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.1–0.2 mg/kg | single dose | Sedation | Strong | Walz P. Practical management of pain in cattle. Presented at: ABVP; 2006. PMID: 42126006 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1349 (2026-08-01). |
| IV | 0.05–0.1 mg/kg | single dose | Sedation, analgesia | Strong | Walz P. Practical management of pain in cattle. Presented at: ABVP; 2006. PMID: 42126006 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1349 (2026-08-01). |
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Alpha-2 adrenergic agonist causing dose-dependent sedation, analgesia, and muscle relaxation. Also activates peripheral alpha-2 receptors causing vasoconstriction and bradycardia.
Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Xylazine dose ranges in cattle, with cited source references: IM 0.1–0.2 mg/kg single dose; IV 0.05–0.1 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Xylazine in cattle: IM, IV.
Xylazine is indicated in cattle for: Sedation, Sedation, analgesia.
These are general warnings for Xylazine across species; consult the cattle dosing table above for species-specific guidance. Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Why a species-specific page? Xylazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.