Livestock · Sus scrofa domesticus · typical adult weight 1.00–300.00 kg
Xylazine is dosed at 1–2 mg/kg IM Once in swine, per Edson MC. Anesthesia and surgery of miniature pigs. Presented at: Atlantic Coast Vet Conference (ACVC); 2016. PMID: 40415082; Chigerwe M. Common anesthesia techniques and medication used for management of diseases in companion pigs. Presented at: Pacific Veterinary Conference; 2016. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1350 (2026-08-01). — Plumb's 10th ed (held) printed p.1319, Xylazine monograph spanning p.1319-1323; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Xylazine is used in swine for Sedation, pre-anesthetic. Routes documented in swine: IM. A typical adult swine weighs 1.00–300.00 kg. ExoticRx lists 1 cited dose rule for Xylazine in swine, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rompun, AnaSed
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 1–2 mg/kg | Once | Single dose | Sedation, pre-anesthetic | Moderate | Edson MC. Anesthesia and surgery of miniature pigs. Presented at: Atlantic Coast Vet Conference (ACVC); 2016. PMID: 40415082; Chigerwe M. Common anesthesia techniques and medication used for management of diseases in companion pigs. Presented at: Pacific Veterinary Conference; 2016. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1350 (2026-08-01). — Plumb's 10th ed (held) printed p.1319, Xylazine monograph spanning p.1319-1323; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5–3 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.879 | • 0.5-3 mg/kg IM. (Use in combination with other drugs in swine (e.g., 2 mg/kg |
| 2 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.879 | • 0.5-3 mg/kg IM. (Use in combination with other drugs in swine (e.g., 2 mg/kg |
| 10 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.879 | xylazine 1 10 mg/kg ketamine, administered IM). It is unreliable alone. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your swine's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Alpha-2 adrenergic agonist causing dose-dependent sedation, analgesia, and muscle relaxation. Also activates peripheral alpha-2 receptors causing vasoconstriction and bradycardia.
Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.
Xylazine dose range in swine, with cited source references: IM 1–2 mg/kg Once. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Xylazine in swine: IM.
Cited course lengths for Xylazine in swine include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Xylazine is indicated in swine for: Sedation, pre-anesthetic.
These are general warnings for Xylazine across species; consult the swine dosing table above for species-specific guidance. Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Why a species-specific page? Xylazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.