Xylazine for Swine
Livestock · Sus scrofa domesticus · typical adult weight 1.00–300.00 kg
Xylazine is used in swine for Sedation, pre-anesthetic. Routes documented in swine: IM. A typical adult swine weighs 1.00–300.00 kg. ExoticRx lists 1 cited dose rule for Xylazine in swine, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Rompun, AnaSed
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 1–2 mg/kg | Once | Single dose | Sedation, pre-anesthetic | Moderate | Plumb's Veterinary Drug Handbook |
Need the exact dose for your patient?
These ranges are per kg. Enter your swine's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Alpha-2 adrenergic agonist causing dose-dependent sedation, analgesia, and muscle relaxation. Also activates peripheral alpha-2 receptors causing vasoconstriction and bradycardia.
Side effects & warnings
Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Sedative drugs with swine dosing
Xylazine dosing in other species
Why a species-specific page? Xylazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.