Livestock · Ovis aries · typical adult weight 30.00–120.00 kg
Xylazine is dosed at 0.05–0.1 mg/kg IM As needed in sheep, per Plumb's Veterinary Drug Handbook. Xylazine is used in sheep for Sedation, chemical restraint, Sedation. Routes documented in sheep: IM. A typical adult sheep weighs 30.00–120.00 kg. ExoticRx lists 2 cited dose rules for Xylazine in sheep, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rompun, AnaSed
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.05–0.1 mg/kg | As needed | Single dose | Sedation, chemical restraint | Moderate | Plumb's Veterinary Drug Handbook |
| IM | 0.1–0.2 mg/kg | single dose | — | Sedation |
| Snyder J. Anesthesia and pain management: Minor surgeries. Presented at: Western Veterinary Conference; 2009.; Edmondson MA. Anesthesia and common surgical procedures in small ruminants. Presented at: Southwest Veterinary Symposium (SWVS); 2016. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1350 (2026-08-01). |
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These ranges are per kg. Enter your sheep's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Alpha-2 adrenergic agonist causing dose-dependent sedation, analgesia, and muscle relaxation. Also activates peripheral alpha-2 receptors causing vasoconstriction and bradycardia.
Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Species-specific contraindications and adverse-reaction reports for sheep may differ from canine / feline reference data — consult the primary citations listed with each rule.
Xylazine dose ranges in sheep, with cited source references: IM 0.05–0.1 mg/kg As needed; IM 0.1–0.2 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Xylazine in sheep: IM.
Cited course lengths for Xylazine in sheep include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Xylazine is indicated in sheep for: Sedation, chemical restraint, Sedation.
These are general warnings for Xylazine across species; consult the sheep dosing table above for species-specific guidance. Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Why a species-specific page? Xylazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sheep — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.