Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Romifidine (Injectable) is dosed at 0.04–0.12 mg/kg IV single dose in horses, per SEDIVET - Romifidine Hydrochloride Liquid (Solution) [US Product Label for Horses]. Boehringer lngelheim Animal Health USA Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1157 (2026-08-01).. Romifidine (Injectable) is used in horses for Sedation, preanesthesia, Standing sedation. Routes documented in horses: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Romifidine (Injectable) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sedivet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.04–0.12 mg/kg | single dose | — | Sedation, preanesthesia | Strong | SEDIVET - Romifidine Hydrochloride Liquid (Solution) [US Product Label for Horses]. Boehringer lngelheim Animal Health USA Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1157 (2026-08-01). |
| IV | 0.04–0.12 mg/kg | As needed | Single dose; 30-90 min | Standing sedation | Strong | SEDIVET - Romifidine Hydrochloride Liquid (Solution) [US Product Label for Horses]. Boehringer lngelheim Animal Health USA Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1157 (2026-08-01). |
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These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Alpha-2 adrenoceptor agonist providing sedation and analgesia in horses. Less ataxia compared to xylazine or detomidine at equipotent sedative doses.
For use in horses only. Causes bradycardia and initial hypertension followed by hypotension. Do not use in horses intended for human consumption. IV administration only.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Romifidine (Injectable) dose ranges in horses, with cited source references: IV 0.04–0.12 mg/kg single dose; IV 0.04–0.12 mg/kg As needed. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Romifidine (Injectable) in horses: IV.
Cited course lengths for Romifidine (Injectable) in horses include: Single dose; 30-90 min. Duration depends on the indication — match it to the specific dose rule in the table above.
Romifidine (Injectable) is indicated in horses for: Sedation, preanesthesia, Standing sedation.
These are general warnings for Romifidine (Injectable) across species; consult the horse dosing table above for species-specific guidance. For use in horses only. Causes bradycardia and initial hypertension followed by hypotension. Do not use in horses intended for human consumption. IV administration only.
Why a species-specific page? Romifidine (Injectable) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.