Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Romifidine (Injectable) is dosed at 0.04–0.12 mg/kg IV Once (single slow IV injection) in horses, per SEDIVET - Romifidine Hydrochloride Liquid (Solution) [US Product Label for Horses]. Boehringer lngelheim Animal Health USA Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1157 (2026-08-01). — Plumb's 10th ed (held) printed p.1129, Romifidine monograph spanning p.1129-1130; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Romifidine (Injectable) is used in horses for Standing sedation, Sedation, preanesthesia. Routes documented in horses: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Romifidine (Injectable) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sedivet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.04–0.12 mg/kg | Once (single slow IV injection) | Single dose; 30-90 min | Standing sedation | Strong | SEDIVET - Romifidine Hydrochloride Liquid (Solution) [US Product Label for Horses]. Boehringer lngelheim Animal Health USA Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1157 (2026-08-01). — Plumb's 10th ed (held) printed p.1129, Romifidine monograph spanning p.1129-1130; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| IV | 0.04–0.12 mg/kg | single dose | — | Sedation, preanesthesia | Strong | SEDIVET - Romifidine Hydrochloride Liquid (Solution) [US Product Label for Horses]. Boehringer lngelheim Animal Health USA Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1157 (2026-08-01). — Plumb's 10th ed (held) printed p.1129, Romifidine monograph spanning p.1129-1130; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mcg/kg) | Route | Source | As printed |
|---|---|---|---|
| 40–120 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.744 | • Sedation and analgesia: 40-120 mcg/kg IV. |
| 100 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.744 | • Preanesthetic: 100 mcg/kg IV. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Alpha-2 adrenoceptor agonist providing sedation and analgesia in horses. Less ataxia compared to xylazine or detomidine at equipotent sedative doses.
For use in horses only. Causes bradycardia and initial hypertension followed by hypotension. Do not use in horses intended for human consumption. IV administration only.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Romifidine (Injectable) dose ranges in horses, with cited source references: IV 0.04–0.12 mg/kg Once (single slow IV injection); IV 0.04–0.12 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Romifidine (Injectable) in horses: IV.
Cited course lengths for Romifidine (Injectable) in horses include: Single dose; 30-90 min. Duration depends on the indication — match it to the specific dose rule in the table above.
Romifidine (Injectable) is indicated in horses for: Standing sedation, Sedation, preanesthesia.
These are general warnings for Romifidine (Injectable) across species; consult the horse dosing table above for species-specific guidance. For use in horses only. Causes bradycardia and initial hypertension followed by hypotension. Do not use in horses intended for human consumption. IV administration only.
Why a species-specific page? Romifidine (Injectable) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.