Chlorpromazine for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Chlorpromazine is used in dog for Antiemetic, pre-anesthetic sedation. Routes documented in dog: IM. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Chlorpromazine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Thorazine
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.5–1 mg/kg | q6-8h | Short-term | Antiemetic, pre-anesthetic sedation | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Blocks dopamine D2 receptors in the CRTZ (antiemetic) and CNS (sedation). Also has anticholinergic, antihistaminic, and alpha-adrenergic blocking properties.
Side effects & warnings
Hypotension (alpha blockade). Antiemetic. Sedation without analgesia. Lowers seizure threshold. Avoid in dehydrated or hypovolemic patients.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Sedative drugs with dog dosing
Why a species-specific page? Chlorpromazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.