Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenylpropanolamine is dosed at 1–2 mg/kg PO q8-12h in dogs, per Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), p.634 (PDF 662), Small Animal Dosage — Dogs — LOCATOR CONVENTION 2026-08-07: 'p.634' is the PRINTED page number, confirmed by finding the drug named on it in the held copy. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Phenylpropanolamine is used in dogs for Hormone-responsive urinary incontinence. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phenylpropanolamine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Proin, Propalin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q8-12h | Long-term | Hormone-responsive urinary incontinence | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), p.634 (PDF 662), Small Animal Dosage — Dogs — LOCATOR CONVENTION 2026-08-07: 'p.634' is the PRINTED page number, confirmed by finding the drug named on it in the held copy. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.337 | 0.8 mg phenylpropano- lamine/kg (equivalent to 1 mg/kg phenylpropanolamine hydrochloride/ kg) p.o. q8h or 1.2 mg/kg phenylpropanolamine/kg (equi |
| 1.2 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.337 | 1 mg/kg phenylpropanolamine hydrochloride/ kg) p.o. q8h or 1.2 mg/kg phenylpropanolamine/kg (equivalent to 1.5 mg/kg phenylpropanolamine hydrochloride/kg) p.o |
| 1.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.337 | p.o. q8h or 1.2 mg/kg phenylpropanolamine/kg (equivalent to 1.5 mg/kg phenylpropanolamine hydrochloride/kg) p.o. q12h |
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Alpha-1 adrenergic agonist increasing urethral sphincter tone. First-line treatment for hormone-responsive urinary incontinence in spayed females.
FDA-approved for dogs (Proin). Hypertension, tachycardia, restlessness, anorexia possible. Monitor blood pressure. Contraindicated with concurrent MAO inhibitors.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phenylpropanolamine dose range in dogs, with cited source references: PO 1–2 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phenylpropanolamine in dogs: PO.
Cited course lengths for Phenylpropanolamine in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Phenylpropanolamine is indicated in dogs for: Hormone-responsive urinary incontinence.
These are general warnings for Phenylpropanolamine across species; consult the dog dosing table above for species-specific guidance. FDA-approved for dogs (Proin). Hypertension, tachycardia, restlessness, anorexia possible. Monitor blood pressure. Contraindicated with concurrent MAO inhibitors.
Why a species-specific page? Phenylpropanolamine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.662 | • 1 mg/kg q8h PO. Increase dose to 1.5-2 mg/kg q8h PO if necessary. In some |
| 1.5–2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.662 | • 1 mg/kg q8h PO. Increase dose to 1.5-2 mg/kg q8h PO if necessary. In some |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.