Mannitol for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Mannitol is used in dog for Cerebral edema, acute glaucoma, oliguric renal failure. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Mannitol in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Osmitrol
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.5–2 g/kg | q4-6h (max 3 doses in 24h) | Short-term (24-48h) | Cerebral edema, acute glaucoma, oliguric renal failure | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Osmotic diuretic that draws water from intracellular and interstitial spaces into the intravascular compartment. Reduces intracranial and intraocular pressure.
Side effects & warnings
Used for cerebral edema, acute glaucoma, and oliguric renal failure. Administer through filter (may crystallize). May cause volume overload initially. CONTRAINDICATED in pulmonary edema, dehydration, anuria.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Urinary drugs with dog dosing
Mannitol dosing in other species
Why a species-specific page? Mannitol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.