Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Mannitol is dosed at 0.5–2 g/kg IV q4-6h (max 3 doses in 24h) in dogs, per BSAVA Small Animal Formulary, 10th Ed, Part A, Mannitol, p.242 (corpus PDF p.258); corroborated by Papich, Saunders Handbook of Veterinary Drugs, Mannitol, p.471 (corpus PDF p.499). Mannitol is used in dogs for Cerebral edema, acute glaucoma, oliguric renal failure. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Mannitol in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Osmitrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.5–2 g/kg | q4-6h (max 3 doses in 24h) | Short-term (24-48h) | Cerebral edema, acute glaucoma, oliguric renal failure | Strong | BSAVA Small Animal Formulary, 10th Ed, Part A, Mannitol, p.242 (corpus PDF p.258); corroborated by Papich, Saunders Handbook of Veterinary Drugs, Mannitol, p.471 (corpus PDF p.499) |
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Osmotic diuretic that draws water from intracellular and interstitial spaces into the intravascular compartment. Reduces intracranial and intraocular pressure.
Used for cerebral edema, acute glaucoma, and oliguric renal failure. Administer through filter (may crystallize). May cause volume overload initially. CONTRAINDICATED in pulmonary edema, dehydration, anuria.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Mannitol dose range in dogs, with cited source references: IV 0.5–2 g/kg q4-6h (max 3 doses in 24h). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Mannitol in dogs: IV.
Cited course lengths for Mannitol in dogs include: Short-term (24-48h). Duration depends on the indication — match it to the specific dose rule in the table above.
Mannitol is indicated in dogs for: Cerebral edema, acute glaucoma, oliguric renal failure.
These are general warnings for Mannitol across species; consult the dog dosing table above for species-specific guidance. Used for cerebral edema, acute glaucoma, and oliguric renal failure. Administer through filter (may crystallize). May cause volume overload initially. CONTRAINDICATED in pulmonary edema, dehydration, anuria.
Why a species-specific page? Mannitol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.