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Benazepril-Amlodipine for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Benazepril-Amlodipine is used in dog for CKD with proteinuria and hypertension. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Benazepril-Amlodipine in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Amodip Plus

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO0.25–0.5 mg/kgq12-24hLong-term; titrate based on UPC and BP responseCKD with proteinuria and hypertensionModerateIRIS CKD Treatment Guidelines; Plumb's 9th Ed

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Mechanism of action

Benazepril (ACE inhibitor) reduces glomerular pressure while amlodipine (calcium channel blocker) reduces systemic hypertension, providing dual renoprotection.

Side effects & warnings

Monitor blood pressure and renal values. May cause hypotension. Adjust dose in dehydrated patients. Common in feline CKD management.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Urinary drugs with dog dosing

Benazepril-Amlodipine dosing in other species

Why a species-specific page? Benazepril-Amlodipine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.