Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Diethylstilbestrol is used in dog for Hormone-responsive urinary incontinence. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Diethylstilbestrol in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: DES
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–1 mg per dog | q24h x 5 days, then q3-7 days | Long-term maintenance | Hormone-responsive urinary incontinence | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic non-steroidal estrogen that increases urethral sphincter tone and sensitivity to alpha-adrenergic stimulation. Treats hormone-responsive incontinence.
Aplastic anemia risk with high or prolonged doses. Use lowest effective dose. Loading then maintenance dosing. Monitor CBC. Feminizing effects in males.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Diethylstilbestrol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.