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Benazepril-Amlodipine

Amodip Plus

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Urinary

Routes

PO

Indications

CKD

Mechanism of Action

Benazepril (ACE inhibitor) reduces glomerular pressure while amlodipine (calcium channel blocker) reduces systemic hypertension, providing dual renoprotection.

Side effects & warnings

Monitor blood pressure and renal values. May cause hypotension. Adjust dose in dehydrated patients. Common in feline CKD management.

Species with Benazepril-Amlodipine dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Moderate×1Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

  • · IRIS CKD Treatment Guidelines; Plumb's 9th Ed
  • · ISFM Consensus Guidelines on CKD; Plumb's 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Cat (Domestic)PO0.5–1 mg/kgq24hStrongISFM Consensus Guidelines on CKD; Plumb's 9th Ed
Dog (Domestic)PO0.25–0.5 mg/kgq12-24hModerateIRIS CKD Treatment Guidelines; Plumb's 9th Ed

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