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Aluminum Hydroxide Gel

Amphojel, AlternaGEL

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Urinary

Routes

PO

Indications

Hyperphosphatemia (CKD)

Mechanism of Action

Binds dietary phosphate in the GI tract forming insoluble aluminum phosphate, preventing absorption and reducing serum phosphorus levels.

Side effects & warnings

Constipation common. Long-term use may cause aluminum accumulation. Mix with food for best phosphate binding. Monitor serum phosphorus.

Species with Aluminum Hydroxide Gel dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Strong×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO30–90 mg/kgq8-12h with mealsStrongPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO30–90 mg/kgq8-12h with mealsStrongPlumb's Veterinary Drug Handbook, 9th Ed

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