Cat · Felis catus · typical adult weight 2.50–7.00 kg
Mannitol is dosed at 0.5–1.5 g/kg IV q4-6h in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.793, Mannitol monograph spanning p.793-795; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.795, Mannitol monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Mannitol is used in cats for Cerebral edema, acute glaucoma. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Mannitol in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Osmitrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.5–1.5 g/kg | q4-6h | Short-term | Cerebral edema, acute glaucoma |
| Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.793, Mannitol monograph spanning p.793-795; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.795, Mannitol monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (g/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.25–2 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.258 | 0.25-2 g/kg i.v. infusion of 15-20% solution. There is some evidence that higher doses have greater |
| 0.25–1 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.258 | ffect, but lower doses allow for repeated boluses. Doses of 0.25-1.0 g/kg are recommended. The dose is given over 20-30 min. The dose may be repeated on |
| 0.5–2 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.258 | • Acute glaucoma (if refractory to topical treatments): 0.5-2 g/kg i.v. infusion over 30 min. Withholding water for the first few hours after adm |
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Osmotic diuretic that draws water from intracellular and interstitial spaces into the intravascular compartment. Reduces intracranial and intraocular pressure.
Used for cerebral edema, acute glaucoma, and oliguric renal failure. Administer through filter (may crystallize). May cause volume overload initially. CONTRAINDICATED in pulmonary edema, dehydration, anuria.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Mannitol dose range in cats, with cited source references: IV 0.5–1.5 g/kg q4-6h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Mannitol in cats: IV.
Cited course lengths for Mannitol in cats include: Short-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Mannitol is indicated in cats for: Cerebral edema, acute glaucoma.
These are general warnings for Mannitol across species; consult the cat dosing table above for species-specific guidance. Used for cerebral edema, acute glaucoma, and oliguric renal failure. Administer through filter (may crystallize). May cause volume overload initially. CONTRAINDICATED in pulmonary edema, dehydration, anuria.
Why a species-specific page? Mannitol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 0.25–0.5 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.258 | failure (as an alternative to using furosemide): 0.25-0.5 g/kg i.v. infusion over 5-10 min. If successful can repeat in 4 hours. Rehydrate the patient p |
| 0.5 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.499 | • Fluid expansion: 0.5 g/kg to 0.8 g/kg IV over 5 minutes, followed by CRI of |
| 0.8 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.499 | • Fluid expansion: 0.5 g/kg to 0.8 g/kg IV over 5 minutes, followed by CRI of |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 1 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.499 | 1 mg/kg/min. M |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.