ExoticRx · exoticrx.com/drugs/phenylpropanolamine
US brand names:Proin, Propalin
Phenylpropanolamine is dosed at 1–2 mg/kg PO q8-12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Alpha-1 adrenergic agonist increasing urethral sphincter tone. First-line treatment for hormone-responsive urinary incontinence in spayed females.
FDA-approved for dogs (Proin). Hypertension, tachycardia, restlessness, anorexia possible. Monitor blood pressure. Contraindicated with concurrent MAO inhibitors.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q8-12h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.