ExoticRx · exoticrx.com/drugs/phenylpropanolamine
US brand names:Proin, Propalin
Phenylpropanolamine is dosed at 1–2 mg/kg PO q8-12h in dogs, per Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), p.634 (PDF 662), Small Animal Dosage — Dogs — LOCATOR CONVENTION 2026-08-07: 'p.634' is the PRINTED page number, confirmed by finding the drug named on it in the held copy. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Verify against current literature before clinical use.
Alpha-1 adrenergic agonist increasing urethral sphincter tone. First-line treatment for hormone-responsive urinary incontinence in spayed females.
FDA-approved for dogs (Proin). Hypertension, tachycardia, restlessness, anorexia possible. Monitor blood pressure. Contraindicated with concurrent MAO inhibitors.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q8-12h | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), p.634 (PDF 662), Small Animal Dosage — Dogs — LOCATOR CONVENTION 2026-08-07: 'p.634' is the PRINTED page number, confirmed by finding the drug named on it in the held copy. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
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