Marbofloxacin for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Marbofloxacin is used in dog for Severe systemic infections, Skin infections, UTI, respiratory, Complicated UTI (Pseudomonas), Otitis externa (systemic component). Routes documented in dog: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 5 cited dose rules for Marbofloxacin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Zeniquin
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2–5 mg/kg | q24h | Until oral feasible | Severe systemic infections | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 2.75–5.5 mg/kg | q24h | 7-14 days | Skin infections, UTI, respiratory | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 5.5 mg/kg | q24h | 14-28 days | Complicated UTI (Pseudomonas) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 2.75–5.5 mg/kg | q24h | 14-21 days | Otitis externa (systemic component) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 5.5 mg/kg | q24h | 6-8 weeks | Deep pyoderma (Pseudomonas-associated) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal.
Side effects & warnings
Avoid in growing animals (cartilage damage). May lower seizure threshold. Avoid concurrent NSAIDs in dehydrated patients.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antibiotic drugs with dog dosing
Marbofloxacin dosing in other species
Why a species-specific page? Marbofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.