Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Marbofloxacin is dosed at 2 mg/kg IV q24h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.796, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — BSAVA Small Animal Formulary, 10th ed, Part A — Canine and Feline, Marbofloxacin, DOSES, printed p.243 (corpus PDF p.259): "Dogs: Oral and parenteral: 2 mg/kg i.v., s.c., p.o. q24h."; Formulations, printed p.242: "Injectable: 200 mg powder for reconstitution giving 10 mg/ml when reconstituted." [CEILING REDUCED 2026-08-12, two readers — Plumb's printed p.796-798 prints every canine marbofloxacin dose as oral and lists no injectable product, stating "Parenteral formulation is not available in the United States"; Papich printed p.473 likewise prints oral figures only; DailyMed carries no US marbofloxacin injectable label. No retrieved document prints 5 mg/kg IV for a dog.] — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705. Marbofloxacin is used in dogs for Severe systemic infections, Skin infections, UTI, respiratory, Complicated UTI (Pseudomonas). Routes documented in dogs: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 3 cited dose rules for Marbofloxacin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zeniquin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2 mg/kg | q24h | Until oral feasible | Severe systemic infections | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.796, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — BSAVA Small Animal Formulary, 10th ed, Part A — Canine and Feline, Marbofloxacin, DOSES, printed p.243 (corpus PDF p.259): "Dogs: Oral and parenteral: 2 mg/kg i.v., s.c., p.o. q24h."; Formulations, printed p.242: "Injectable: 200 mg powder for reconstitution giving 10 mg/ml when reconstituted." [CEILING REDUCED 2026-08-12, two readers — Plumb's printed p.796-798 prints every canine marbofloxacin dose as oral and lists no injectable product, stating "Parenteral formulation is not available in the United States"; Papich printed p.473 likewise prints oral figures only; DailyMed carries no US marbofloxacin injectable label. No retrieved document prints 5 mg/kg IV for a dog.] — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |
| PO | 2.75–5.5 mg/kg | q24h | 7-14 days | Skin infections, UTI, respiratory | Strong | ZENIQUIN - Marbofloxacin Tablet [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.824 (2026-08-01). — Plumb's 10th ed (held) printed p.797, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 2 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.259 | 2 mg/kg i.v., s.c., p.o. q24h. Higher doses should be considered for certain sites, including in |
| 2.75–5.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.501 | • 2.75-5.5 mg/kg once daily PO. • 2.75-5.5 mg/kg once daily PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal.
Avoid in growing animals (cartilage damage). May lower seizure threshold. Avoid concurrent NSAIDs in dehydrated patients.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Marbofloxacin dose ranges in dogs, with cited source references: IV 2 mg/kg q24h; PO 2.75–5.5 mg/kg q24h; PO 5.5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Marbofloxacin in dogs: IV, PO.
Cited course lengths for Marbofloxacin in dogs include: Until oral feasible; 7-14 days; 14-28 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Marbofloxacin is indicated in dogs for: Severe systemic infections, Skin infections, UTI, respiratory, Complicated UTI (Pseudomonas).
These are general warnings for Marbofloxacin across species; consult the dog dosing table above for species-specific guidance. Avoid in growing animals (cartilage damage). May lower seizure threshold. Avoid concurrent NSAIDs in dehydrated patients.
Why a species-specific page? Marbofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| PO | 5.5 mg/kg | q24h | 14-28 days | Complicated UTI (Pseudomonas) | Strong | Cole L. Pseudomonas otitis: diagnosis, treatment, and prognosis. Presented at: AVA; 2008. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.824 (2026-08-01). — Plumb's 10th ed (held) printed p.797, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |