Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.
Marbofloxacin is dosed at 2–5 mg/kg PO q24h in rabbits, per Carpenter JW, Pollock CG, Koch DE, et al. Single- and multiple-dose pharmacokinetics of marbofloxacin after oral administration to rabbits. Am J Vet Res. 2009;70:522-526. Verify against current literature before clinical use.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Sample dosing (2 of 26 cited rules)
A dog/cat sample is shown here. Cited dosing for all 20 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Cole L. Pseudomonas otitis: diagnosis, treatment, and prognosis. Presented at: AVA; 2008. — Plumb's 10th ed printed p.797, Marbofloxacin monograph spanning p.796-798.Compilation only — we have not located an independent source that prints this figure.
· 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.772 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).
· Abo-EL-Sooud K, Swielim GA, EL-Gammal SM, et al. Comparative Pharmacokinetics and bioavailability of marbofloxacin in geese (Anser anser domesticus) after two sites of intramuscular administrations. J Vet Pharmacol Ther. 2020;43(4):313-318. doi:10.1111/jvp.12853https://europepmc.org/article/MED/32162309 — PRINTED DETAIL MISSING FROM THIS RULE (retrieved 2026-08-19): We recommend the thigh muscle as IM site of injection to obtain maximum concentrations of the administered drug in geese. — Abo-El-Sooud et al, J Vet Pharmacol Ther 2020;43(4):313-318, PMID 32162309; missing: 21 CFR 530.41(a) "The following drugs … are prohibited for extralabel animal and human drug uses in food-producing animals" — "(10) Fluoroquinolones"
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· Carpenter Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds), Marbofloxacin block. The row is printed for BLUE AND GOLD MACAWS and is framed /PK. 146. Carpenter JW, Hunter RP, Olsen JH, et al. Pharmacokinetics of marbofloxacin in blue and gold macaws (Ara ararauna). Am J Vet Res. 2006 -- 67:947-950. EXTRAPOLATED to African grey parrot: no held text prints a marbofloxacin dose for Psittacus erithacus.
· Carpenter JW, Hunter RP, Olsen JH, et al. Pharmacokinetics of marbofloxacin in blue and gold macaws (Ara ararauna). Am J Vet Res. 2006;67:947-950. doi:10.2460/ajvr.67.6.947
· Carpenter JW, Pollock CG, Koch DE, et al. Single- and multiple-dose pharmacokinetics of marbofloxacin after oral administration to rabbits. Am J Vet Res. 2009;70:522-526. doi:10.2460/ajvr.70.4.522
· Coke RL, Isaza R, Koch DE, et al. Preliminary single-dose pharmacokinetics of marbofloxacin in ball pythons (Python regius). J Zoo Wildl Med. 2006;37:6-10. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.217 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). — CORROBORATED 2026-08-06 by independent literature: Preliminary single-dose pharmacokinetics of marbofloxacin in ball pythons (Python regius). (Journal of zoo and wildlife medicine: official publication of the American Association of Zoo Veterinarians, 2006). doi:10.1638/04-102.1. https://doi.org/10.1638/04-102.1. The paper reports this drug at this dose in this species: "adult ball pythons (Python regius) was determined after i.v. and p.o. administration of a single […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct.
· Cole L. Pseudomonas otitis: diagnosis, treatment, and prognosis. Presented at: AVA; 2008. — Plumb's 10th ed printed p.797, Marbofloxacin monograph spanning p.796-798.
· Hedley J. BSAVA Small Animal Formulary. Part B: Exotic Pets, 10th ed., British Small Animal Veterinary Association — Carpenter's Exotic Animal Formulary 6th ed, Table 7.1 (Antimicrobial and Antifungal Agents Used in Sugar Gliders).
· Lai OR, Marin P, Laricchiuta P, et al. Pharmacokinetics of injectable marbofloxacin after intravenous and intramuscular administration in red-eared sliders (Trachemys scripta elegans). J Vet Pharmacol Ther. 2020;43:129-134. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.218 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). — CORROBORATED 2026-08-06 by independent literature: Pharmacokinetics of injectable marbofloxacin after intravenous and intramuscular administration in red-eared sliders (Trachemys scripta elegans). (Journal of veterinary pharmacology and therapeutics, 2020). doi:10.1111/jvp.12803. https://doi.org/10.1111/jvp.12803. The paper reports this drug at this dose in this species: "of their broad spectrum of activity including the most frequent pathogens of these species. The […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct. — INTERVAL IS PRINTED: Mader's Reptile Medicine and Surgery 3rd ed, Table 116.7 ("Peer-Reviewed Fluoroquinolones Pharmacokinetic Data in Reptile Species to Utilize in Clinical Practice"), printed p.1152 — red-eared slider, 2 mg/kg, IV and IM, "Recommended Frequency of Administration 24 hrs".
· Lai OR, Marín P, Laricchiuta P, Gelli D, Escudero E, Crescenzo G. Pharmacokinetics of injectable marbofloxacin after intravenous and intramuscular administration in red-eared sliders (Trachemys scripta elegans). J Vet Pharmacol Ther. 2020;43(2):129-134. doi:10.1111/jvp.12803https://europepmc.org/abstract/MED/31393637 — INTERVAL IS PRINTED: Mader's Reptile Medicine and Surgery 3rd ed, Table 116.7 ("Peer-Reviewed Fluoroquinolones Pharmacokinetic Data in Reptile Species to Utilize in Clinical Practice"), printed p.1152 — red-eared slider, 2 mg/kg, IV and IM, "Recommended Frequency of Administration 24 hrs".
· Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).
· Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.772 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).
· Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.796, Marbofloxacin monograph spanning p.796-798.
· Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.796, Marbofloxacin monograph spanning p.796-798. — BSAVA Small Animal Formulary, 10th ed, Part A — Canine and Feline, Marbofloxacin, DOSES, printed p.243: "Dogs: Oral and parenteral: 2 mg/kg i.v., s.c., p.o. q24h."; Formulations, printed p.242: "Injectable: 200 mg powder for reconstitution giving 10 mg/ml when reconstituted."
· Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.654. Row as printed binds this dose to raptors on its own line: "Marbofloxacin Marbocyl 2% and Raptors IV, IM, PO 5-10 mg/kg bid for 5-7 d As for enrofloxacin but less likely to cause".
Antibiotic, analgesic, anesthetic, and dental-disease dosing for Chinchilla lanigera. Same dysbiosis warnings as rabbits, plus the chinchilla-specific sensitivities to anesthesia and stress that change post-op care.
Marbofloxacin (Zeniquin) Dosage for Rabbits, Mice | ExoticRx