Cat · Felis catus · typical adult weight 2.50–7.00 kg
Marbofloxacin is dosed at 2–5 mg/kg IV q24h in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.796, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Marbofloxacin is used in cats for Severe systemic infections, Feline lower urinary tract disease (bacterial), Skin infections, UTI. Routes documented in cats: IV, PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 3 cited dose rules for Marbofloxacin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zeniquin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2–5 mg/kg | q24h | Until oral feasible | Severe systemic infections | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.796, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 2.75–5.5 mg/kg | q24h | 10-14 days | Feline lower urinary tract disease (bacterial) | Strong | ZENIQUIN - Marbofloxacin Tablet [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=05196313-2371-45ad-a6fb-6269f8ef94c5 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.825 (2026-08-01). — Plumb's 10th ed (held) printed p.797, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 2.75–5.5 mg/kg | q24h | 7-14 days | Skin infections, UTI | Strong | ZENIQUIN - Marbofloxacin Tablet [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=05196313-2371-45ad-a6fb-6269f8ef94c5 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.825 (2026-08-01). — Plumb's 10th ed (held) printed p.797, Marbofloxacin monograph spanning p.796-798; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 2 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.259 | 2 mg/kg i.v., s.c., p.o. q24h. 244 BSAVA Small Animal Formulary 10th edition: Part A - Canine |
| 2.75–5.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.501 | • 2.75-5.5 mg/kg once daily PO. • 2.75-5.5 mg/kg once daily PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal.
Avoid in growing animals (cartilage damage). May lower seizure threshold. Avoid concurrent NSAIDs in dehydrated patients.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Marbofloxacin dose ranges in cats, with cited source references: IV 2–5 mg/kg q24h; PO 2.75–5.5 mg/kg q24h; PO 2.75–5.5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Marbofloxacin in cats: IV, PO.
Cited course lengths for Marbofloxacin in cats include: Until oral feasible; 10-14 days; 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Marbofloxacin is indicated in cats for: Severe systemic infections, Feline lower urinary tract disease (bacterial), Skin infections, UTI.
These are general warnings for Marbofloxacin across species; consult the cat dosing table above for species-specific guidance. Avoid in growing animals (cartilage damage). May lower seizure threshold. Avoid concurrent NSAIDs in dehydrated patients.
Why a species-specific page? Marbofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.