Cat · Felis catus · typical adult weight 2.50–7.00 kg
Marbofloxacin is dosed at 2–5 mg/kg IV q24h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Marbofloxacin is used in cats for Severe systemic infections, Feline lower urinary tract disease (bacterial), Skin infections, UTI. Routes documented in cats: IV, PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 3 cited dose rules for Marbofloxacin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zeniquin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2–5 mg/kg | q24h | Until oral feasible | Severe systemic infections | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 2.75–5.5 mg/kg | q24h | 10-14 days | Feline lower urinary tract disease (bacterial) | Strong | ZENIQUIN - Marbofloxacin Tablet [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=05196313-2371-45ad-a6fb-6269f8ef94c5 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.825 (2026-08-01). |
| PO | 2.75–5.5 mg/kg | q24h | 7-14 days | Skin infections, UTI | Strong | ZENIQUIN - Marbofloxacin Tablet [US Product Label for Dogs and Cats]. Zoetis Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=05196313-2371-45ad-a6fb-6269f8ef94c5 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.825 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal.
Avoid in growing animals (cartilage damage). May lower seizure threshold. Avoid concurrent NSAIDs in dehydrated patients.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Marbofloxacin dose ranges in cats, with cited source references: IV 2–5 mg/kg q24h; PO 2.75–5.5 mg/kg q24h; PO 2.75–5.5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Marbofloxacin in cats: IV, PO.
Cited course lengths for Marbofloxacin in cats include: Until oral feasible; 10-14 days; 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Marbofloxacin is indicated in cats for: Severe systemic infections, Feline lower urinary tract disease (bacterial), Skin infections, UTI.
These are general warnings for Marbofloxacin across species; consult the cat dosing table above for species-specific guidance. Avoid in growing animals (cartilage damage). May lower seizure threshold. Avoid concurrent NSAIDs in dehydrated patients.
Why a species-specific page? Marbofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.