Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Insulin Glargine is dosed at 0.25–0.5 IU/kg SC q12h in dogs, per Hess RS, Drobatz KJ. Glargine insulin for treatment of naturally occurring diabetes mellitus in dogs. J Am Vet Med Assoc. 2013;243:1154-1161. doi:10.2460/javma.243.8.1154; Fracassi F, Boretti FS, Sieber-Ruckstuhl NS, Reusch CE. Use of insulin glargine in dogs with diabetes mellitus. Vet Rec. 2012;170:52-U107. doi:10.1136/vr.100070 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.687 (2026-08-01).. Insulin Glargine is used in dogs for Diabetes mellitus. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Insulin Glargine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lantus, Basaglar
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 0.25–0.5 IU/kg | q12h | Lifelong; adjust based on glucose curves | Diabetes mellitus |
| Hess RS, Drobatz KJ. Glargine insulin for treatment of naturally occurring diabetes mellitus in dogs. J Am Vet Med Assoc. 2013;243:1154-1161. doi:10.2460/javma.243.8.1154; Fracassi F, Boretti FS, Sieber-Ruckstuhl NS, Reusch CE. Use of insulin glargine in dogs with diabetes mellitus. Vet Rec. 2012;170:52-U107. doi:10.1136/vr.100070 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.687 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Long-acting insulin analogue that forms microprecipitates in subcutaneous tissue, providing slow sustained release with relatively peakless absorption over ~24 hours.
Hypoglycemia risk. Do not dilute or mix with other insulins. Preferred for diabetic cats. Dose based on glucose curves.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Insulin Glargine dose range in dogs, with cited source references: SC 0.25–0.5 IU/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Insulin Glargine in dogs: SC.
Cited course lengths for Insulin Glargine in dogs include: Lifelong; adjust based on glucose curves. Duration depends on the indication — match it to the specific dose rule in the table above.
Insulin Glargine is indicated in dogs for: Diabetes mellitus.
These are general warnings for Insulin Glargine across species; consult the dog dosing table above for species-specific guidance. Hypoglycemia risk. Do not dilute or mix with other insulins. Preferred for diabetic cats. Dose based on glucose curves.
Why a species-specific page? Insulin Glargine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.