Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phytosphingosine is used in dogs for Atopic dermatitis (skin barrier support). Routes documented in dogs: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phytosphingosine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Douxo
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | See the cited source for the printed regimen | Mousse/spray q3 days; shampoo 2-3x weekly | Long-term | Atopic dermatitis (skin barrier support) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1424, Phytosphingosine, Topical monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — Plumb's Veterinary Drug Handbook, 10th ed (held), Phytosphingosine, Topical monograph, printed p.1424 (corpus PDF p.1451), Suggested Dosages/Uses: "Phytosphingosine spray should be applied every 3 days for 2 to 3 weeks. ... Mousse ... should be […]" [FREQUENCY CORRECTED 2026-08-12, two readers — no 7-day interval is printed in the monograph.] |
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Naturally occurring sphingolipid that restores skin barrier function. Anti-inflammatory and antimicrobial properties. Precursor to ceramides.
Generally very safe. Used for atopic dermatitis, seborrhea, and skin barrier support. Adjunctive therapy. No significant adverse effects reported.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phytosphingosine dose range in dogs, with cited source references: Topical See the cited source for the printed regimen Mousse/spray q3 days; shampoo 2-3x weekly. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phytosphingosine in dogs: Topical.
Cited course lengths for Phytosphingosine in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Phytosphingosine is indicated in dogs for: Atopic dermatitis (skin barrier support).
These are general warnings for Phytosphingosine across species; consult the dog dosing table above for species-specific guidance. Generally very safe. Used for atopic dermatitis, seborrhea, and skin barrier support. Adjunctive therapy. No significant adverse effects reported.
Why a species-specific page? Phytosphingosine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.