ExoticRx · exoticrx.com/drugs/phytosphingosine
US brand names:Douxo
Naturally occurring sphingolipid that restores skin barrier function. Anti-inflammatory and antimicrobial properties. Precursor to ceramides.
Generally very safe. Used for atopic dermatitis, seborrhea, and skin barrier support. Adjunctive therapy. No significant adverse effects reported.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Topical | See the cited source for the printed regimen | Mousse/spray q3 days; shampoo 2-3x weekly | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.1424, Phytosphingosine, Topical monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — Plumb's Veterinary Drug Handbook, 10th ed (held), Phytosphingosine, Topical monograph, printed p.1424 (corpus PDF p.1451), Suggested Dosages/Uses: "Phytosphingosine spray should be applied every 3 days for 2 to 3 weeks. ... Mousse ... should be […]" [FREQUENCY CORRECTED 2026-08-12, two readers — no 7-day interval is printed in the monograph.] |
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