Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tranexamic Acid is dosed at 10–20 mg/kg IV Slow IV over 15-20 min; may repeat in 6-8h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) - Tranexamic Acid, Dosages, DOGS, corpus p.1292 — LOCATOR CONVENTION 2026-08-07: the bare 'p.1292' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.1265; verified by finding the drug named there. If you are holding the book, turn to p.1265. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Tranexamic Acid is used in dogs for Hyperfibrinolysis associated with Angiostrongylus vasorum infection. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tranexamic Acid in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cyklokapron, Lysteda
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 10–20 mg/kg | Slow IV over 15-20 min; may repeat in 6-8h | Until bleeding controlled | Hyperfibrinolysis associated with Angiostrongylus vasorum infection | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) - Tranexamic Acid, Dosages, DOGS, corpus p.1292 — LOCATOR CONVENTION 2026-08-07: the bare 'p.1292' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.1265; verified by finding the drug named there. If you are holding the book, turn to p.1265. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 15–20 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.428 | 15-20 mg/kg p.o. q8h; 10 mg/kg i.v. q8h slow i.v. infusion |
| 10 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.428 | 15-20 mg/kg p.o. q8h; 10 mg/kg i.v. q8h slow i.v. infusion |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Synthetic lysine analog that competitively inhibits plasminogen activation, preventing fibrin clot degradation. Stabilizes formed clots.
Used for hemorrhage and coagulopathy. Thrombotic risk — avoid in DIC. Dose-dependent seizure risk (especially in renal disease). Slow IV injection.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tranexamic Acid dose range in dogs, with cited source references: IV 10–20 mg/kg Slow IV over 15-20 min; may repeat in 6-8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tranexamic Acid in dogs: IV.
Cited course lengths for Tranexamic Acid in dogs include: Until bleeding controlled. Duration depends on the indication — match it to the specific dose rule in the table above.
Tranexamic Acid is indicated in dogs for: Hyperfibrinolysis associated with Angiostrongylus vasorum infection.
These are general warnings for Tranexamic Acid across species; consult the dog dosing table above for species-specific guidance. Used for hemorrhage and coagulopathy. Thrombotic risk — avoid in DIC. Dose-dependent seizure risk (especially in renal disease). Slow IV injection.
Why a species-specific page? Tranexamic Acid pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.