ExoticRx · exoticrx.com/drugs/tranexamic-acid
US brand names:Cyklokapron, Lysteda
Tranexamic Acid is dosed at 10–15 mg/kg IV IV slowly in cats, per Padin BR, Fantoni DT. Pilot study to assess intraoperative blood loss in cats after the administration of tranexamic acid during resection of carcinomas and sarcomas. Presented at: International (European) Soc Feline Med (ISFM); 2015. Distributed by John Wiley & Sons, Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1292 (2026-08-01).. Verify against current literature before clinical use.
Synthetic lysine analog that competitively inhibits plasminogen activation, preventing fibrin clot degradation. Stabilizes formed clots.
Used for hemorrhage and coagulopathy. Thrombotic risk — avoid in DIC. Dose-dependent seizure risk (especially in renal disease). Slow IV injection.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Tranexamic Acid CRI dose rule from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 10–25 mg/kgIV slowly, then CRI 10mg/kg/h | Hemorrhage, coagulopathy | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Hemorrhage, coagulopathy
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 10–25 mg/kg | IV slowly, then CRI 10mg/kg/h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 10–15 mg/kg | IV slowly | Weak | Padin BR, Fantoni DT. Pilot study to assess intraoperative blood loss in cats after the administration of tranexamic acid during resection of carcinomas and sarcomas. Presented at: International (European) Soc Feline Med (ISFM); 2015. Distributed by John Wiley & Sons, Inc. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1292 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.