ExoticRx · exoticrx.com/drugs/tranexamic-acid
US brand names:Cyklokapron, Lysteda
Tranexamic Acid is dosed at 10–20 mg/kg IV Slow IV over 15-20 min; may repeat in 6-8h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023) - Tranexamic Acid, Dosages, DOGS, printed p.1265. Verify against current literature before clinical use.
Synthetic lysine analog that competitively inhibits plasminogen activation, preventing fibrin clot degradation. Stabilizes formed clots.
Used for hemorrhage and coagulopathy. Thrombotic risk — avoid in DIC. Dose-dependent seizure risk (especially in renal disease). Slow IV injection.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 10–20 mg/kg | Slow IV over 15-20 min; may repeat in 6-8h | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023) - Tranexamic Acid, Dosages, DOGS, printed p.1265Compilation only — we have not located an independent source that prints this figure. |
| Cat (Domestic) | IV | 10–15 mg/kg | IV slowly | Weak | Padin BR, Fantoni DT. Pilot study to assess intraoperative blood loss in cats after the administration of tranexamic acid during resection of carcinomas and sarcomas. Presented at: International (European) Soc Feline Med (ISFM); 2015. Distributed by John Wiley & Sons, Inc. — Plumb's 10th ed printed p.1264, Tranexamic Acid monograph spanning p.1264-1265.Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.