Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Rivaroxaban is dosed at 1–2 mg/kg PO q24h in dogs, per Swann JW, Garden OA, Fellman CL, et al. ACVIM consensus statement on the treatment of immune-mediated hemolytic anemia in dogs. J Vet Intern Med. 2019;33(3):1141-1172. doi:10.1111/jvim.15463; Blais MC, Bianco D, Goggs R, et al. Consensus on the rational use of antithrombotics in veterinary critical care (CURATIVE): domain 3-defining antithrombotic protocols. J Vet Emerg Crit Care. 2019;29(1):60-74. doi:10.1111/vec.12795 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1150 (2026-08-01).. Rivaroxaban is used in dogs for Thromboembolism prevention. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Rivaroxaban in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Xarelto
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q24h | Long-term; investigational | Thromboembolism prevention | Weak | Swann JW, Garden OA, Fellman CL, et al. ACVIM consensus statement on the treatment of immune-mediated hemolytic anemia in dogs. J Vet Intern Med. 2019;33(3):1141-1172. doi:10.1111/jvim.15463; Blais MC, Bianco D, Goggs R, et al. Consensus on the rational use of antithrombotics in veterinary critical care (CURATIVE): domain 3-defining antithrombotic protocols. J Vet Emerg Crit Care. 2019;29(1):60-74. doi:10.1111/vec.12795 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1150 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Direct, selective factor Xa inhibitor that blocks the conversion of prothrombin to thrombin, preventing fibrin clot formation.
Bleeding risk. No reliable reversal agent in veterinary practice. Monitor for occult bleeding. Limited canine pharmacokinetic data.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Rivaroxaban dose range in dogs, with cited source references: PO 1–2 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Rivaroxaban in dogs: PO.
Cited course lengths for Rivaroxaban in dogs include: Long-term; investigational. Duration depends on the indication — match it to the specific dose rule in the table above.
Rivaroxaban is indicated in dogs for: Thromboembolism prevention.
These are general warnings for Rivaroxaban across species; consult the dog dosing table above for species-specific guidance. Bleeding risk. No reliable reversal agent in veterinary practice. Monitor for occult bleeding. Limited canine pharmacokinetic data.
Why a species-specific page? Rivaroxaban pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.