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Rivaroxaban for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Rivaroxaban is used in dog for Thromboembolism prevention. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Rivaroxaban in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Xarelto

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO1–2 mg/kgq24hLong-term; investigationalThromboembolism preventionWeakVeterinary Hematology Literature Review

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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Direct, selective factor Xa inhibitor that blocks the conversion of prothrombin to thrombin, preventing fibrin clot formation.

Side effects & warnings

Bleeding risk. No reliable reversal agent in veterinary practice. Monitor for occult bleeding. Limited canine pharmacokinetic data.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Cardiovascular drugs with dog dosing

Rivaroxaban dosing in other species

Why a species-specific page? Rivaroxaban pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.